Founded by Prof. Kristyn Masters in 2004, the Masters lab employs techniques from biomaterials, tissue engineering, bioconjugate chemistry, gene editing, and microfabrication, to create in vitro environments that model disease progression. We then apply molecular and cellular biology and computational tools to examine cell/tissue outcomes in these biomimetic culture platforms. Through this approach, we seek to: 1) understand how cells integrate multiple cues to make ‘decisions’ about their fate, and 2) decipher disease pathogenesis and elucidate the key stimuli involved, with the intent of using this knowledge to inform the design of clinical therapies.
Our lab is located in the Department of Biomedical Engineering at the University of Wisconsin, in the beautiful city of Madison, Wisconsin. Frequently named one of the best cities in the U.S. (and even one of the Top 10 Happiest Cities in the world!), Madison provides an amazing assortment of outdoor activities, cultural events, restaurants, and pretty much anything else that you might want to do! This is really an awesome and invigorating place to live - come visit us and see!