Selected Peer-Reviewed Publications
for full list, see Google Scholar Profile
Review Articles and Editorials - i.e., summaries of research that we find exciting!
Scott AJ, Simon LR, Hutson HN, Porras AM*, Masters KS*. Engineering the aortic valve extracellular matrix through stages of development, aging, and disease. J Mol Cell Cardiol, 2021; 161:1-8. (PMC8629839)
Micek HM, Visetsouk MR, Masters KS, Kreeger PK*. Engineering the Extracellular Matrix to Model the Evolving Tumor Microenvironment. iScience, 2020; 23(11): 101742. (PMC7666341)
Simon LR, Masters KS*. Disease-inspired tissue engineering: Investigation of cardiovascular pathologies. AACS Biomat Sci Eng, 2020; 6(5): 2518-2532. (PMC7508300). (Invited review for “Leaders in Biomedical Engineering” issue)
Kreeger PK, Strong LE, Masters KS*. Engineering Approaches to Study Cellular Decision-Making (invited). Annu Rev Biomed Eng, 2018; 20:49–72 (PMC6327838)
Porras AM, McCoy CM, Masters KS*. Calcific Aortic Valve Disease: A Battle of the Sexes. Circ Res, 2017, 140:604-606. (PMC5319688)
Porras AM, Hutson HN, Berger AJ, Masters KS*. Engineering approaches to study fibrosis in 3-D in vitro systems. Curr Opin Biotechnol, 2016; 40: 24-30. (PMC4975659)
Rajamannan NM*, Evans F, Aikawa E, Grande-Allen KJ, Demer L, Heistad D, Simmons C, Masters KS, Mathieu P, O’Brien KD, Schoen F, Towler D, Yoganathan A, Otto CM. Calcific Aortic Valve Disease: Not Simply a Degenerative Process: A Review and Agenda for Research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Circulation, 2011;124:1783-1791. (PMC3306614)
Heart Valve Disease
Nelson V, Patil V, Simon LR, Schmidt K, McCoy CM, Masters KS*. Angiogenic Secretion Profile of Valvular Interstitial Cells Varies with Cellular Sex and Phenotype. Front Cardiovasc Med, 2021; 8:736303. (PMC8435671)
Porras AM, Westlund JA, Evans AD, Masters KS*. Creation of Disease-Inspired Biomaterial Environments to Mimic Pathological Events in Early Calcific Aortic Valve Disease. Proc Natl Acad Sci USA, 2018; 115:E363-E371. (PMC5776956) Press Release
Porras AM, Engeland NCA, Marchbanks E, McCormack A, Bouten CVC, Yacoub MH, Latif N*, Masters KS*. Robust Generation of Quiescent Porcine Valvular Interstitial Cell Cultures. J Am Heart Assoc, 2017; 6: pii: e005041. doi: 10.1161/JAHA.116.005041. (PMC5524027)
Hutson HN, Marohl T, Anderson M, Eliceiri K, Campagnola P, Masters KS*. Calcific Aortic Valve Disease is Associated with Layer-Specific Alterations in Collagen Architecture. PLoS One, 2016; 11: e0163858. doi: 10.1371/journal.pone.0163858 (PMC5042542)
Porras AM, Shanmuganayagam D, Meudt JJ, Kreuger CG, Hacker T, Rahko PS, Reed JD, Masters KS*. Development of Aortic Valve Disease in Familial Hypercholesterolemic Swine: Implications for Elucidating Disease Etiology. J Am Heart Assoc, 2015, 4: pii: e002254. (PMC4845146)
McCoy CM, Nicholas DQ, Masters KS*. Sex-Related Differences in Gene Expression by Porcine Aortic Valvular Interstitial Cells, PLoS ONE, 2012;7:e39980. (PMC3393722)
Rodriguez KJ, Piechura LM, Masters KS*. Regulation of valvular interstitial cell phenotype and function by hyaluronic acid in 2-D and 3-D culture environments. Matrix Biol, 2011;30:70-82. (PMC3021089)
Dermal Wound Healing
Kim C, Yang X, Jacobsen S, Masters KS*, Kreeger PK*. Leader cell PLCγ1 activation during keratinocyte collective migration is induced by EGFR localization and clustering. Bioeng Transl Med, 2019; 4(3):e10138. (PMC6764804)
Wickert L, Mitchell IP, Masters KS*, Kreeger PK*. Hierarchy of cellular decisions in collective behavior: Implications for wound healing. Sci Rep, 2016; 6: 20139. (PMC4735862)
Kim C, Mitchell IP, Desotell A, Kreeger PK*, Masters KS*. Immobilized EGF Stimulates Persistent, Directed Keratinocyte Migration via Activation of PLCγ1. FASEB J, 2016; 30: 2580-90. (PMC4904288)
Puccinelli TJ, Bertics PJ, Masters KS*. Regulation of Keratinocyte Signaling and Function via Changes in Epidermal Growth Factor Presentation. Acta Biomaterialia, 2010;6:3415-3425. (PMC2910130)
Tumor Microenvironment
Renner C, Gomez C, Visetsouk MR, Taha I, Khan A, McGregor S, Weisman P, Naba A*, Masters KS*, Kreeger PK*. Multi-modal profiling of the extracellular matrix of human fallopian tubes and serous tubal intraepithelial carcinomas. J Histochem Cytochem, 2022; In Press.
Berger AJ, Renner CM, Hale I, Yang X, Ponik SM, Weisman PS, Masters KS*, Kreeger PK*. Scaffold stiffness influences breast cancer cell invasion via EGFR-linked Mena upregulation and matrix remodeling. Matrix Biol, 2020; 85-86: 80-93. (PMC6562577)
Berger AJ, Linsmeier KM, Kreeger PK*, Masters KS*. Decoupling the effects of stiffness and fiber density on cellular behaviors via an interpenetrating network of gelatin-methacrylate and collagen. Biomaterials, 2017; 141: 125-135. (PMC5556948)
Cell-Substrate Interactions and Stem Cell ECM
Laperle A, Hsiao C, Lampe M, Mortier J, Saha K, Palecek SP*, Masters KS*. α-5 Laminin Synthesized by Human Pluripotent Stem Cells Promotes Self-Renewal. Stem Cell Rep, 2015; 5:195-206. (PMC4618661) Free full text Press Release
Laperle AH, Masters KS*, Palecek S*. Influence of substrate composition on human embryonic stem cell differentiation and extracellular matrix production in embryoid bodies. Biotechnol Prog, 2015;31:212-219. (PMC4340738)
Liu R, Vang K, Kreeger PK, Gellman SH*, Masters KS*. An Experimental and Computational Analysis of Cellular Interactions With Nylon-3 Bearing Substrates, J Biomed Res A, 2012;100:2750-2759. (PMC3429641)
Liu R, Chen X, Gellman SH*, Masters KS*. Nylon-3 Polymers That Enable Selective Culture of Endothelial Cells. J Am Chem Soc, 2013;135:16296-16299. (PMC3996459)
Mentoring and Advocacy
Stevens KR*, Masters KS, Imoukhuede PI, Haynes KA, Setton LA, Cosgriff-Hernandez E, Lediju Bell MA, Rangamani P, Sakiyama-Elbert SE, Finley SD, Willits RK, Koppes AN, Chesler NC, Christman KL, Allen JB, Wong JY, El-Samad H, Desai TA, Eniola-Adefeso O*. Fund Black scientists. Cell, 2021; 184(3): 561-565. (PMC33503447)
Kreeger PK*, Brock A, Gibbs HC, Grande-Allen KJ, Huang AH, Masters KS, Rangamani P, Reagan MR, Servoss SL. Ten simple rules for women principal investigators during a pandemic. PLoS Comput Biol, 2020; 16(10): e1008370. (PMC7595267)
Masters KS*, Kreeger PK*. 10 Simple Rules for Developing a Mentor-Mentee Expectations Document, PLoS Comput Biol, 2017; 13(9): e1005709. (PMC5608163)
Pfund C*, House S, Spencer K, Asquith P, Carney P, Masters KS, McGee R, Shanedling J, Vecchiarelli S, Fleming M. A Research Mentor Training Curriculum for Clinical and Translational Researchers, Clin Trans Sci, 2013;6:26-33. (PMC3572855)
Pfund C, Brace C, Branchaw J, Handelsman J, Masters K, Nanney L. Mentor Training for Biomedical Researchers. In: Pfund C. and Handelsman J., eds. Entering Mentoring Series. New York, NY: W.H. Freeman & Co., 2013.